Scleroderma, also called crest disease, is the name for a group of rare diseases that involves the tightening of the skin and connective tissues, according to the Mayo Clinic. The other sweet lady in the picture is our grandmother, Bella Comer. “She died when she was 47 from scleroderma, a disease that I’m part of finding the cure, as a proud board member of the #SclerodermaResearchFoundation – My heart goes out to everyone who has lost someone dear to them. “My sister Gay would’ve been 73 yesterday,” he wrote on January 10, 2020. Saget wrote a tribute to his sister in 2020, around the time of her birthday, sharing a photo of himself with his sister and their grandmother. It may seem silly, but it helped me somehow. Aside from his many creative gifts, he also shared this profound grief. Bob Saget spoke openly & poignantly about loss.